Theological seminaries have a significant role in creating and maintaining the values of the Islamic Revolution. For this reason, the enemies of the Islamic Revolution, in order to advance their goals, sought to turn the seminaries into the cause of the decline and destruction of the Revolution. Therefore, by creating and using the driving forces of the antithesis of the Islamic Revolution in the seminaries, they intend to degenerate and decline the revolution from within the seminaries. In this study, the antithesis of the Islamic Revolution in theological seminaries have been measured by interviewing seminary experts and the method of content analysis. The antithesis drivers of the Islamic Revolution in the seminaries that have been identified and analyzed in this study are: weakening social status, transforming values and principles of the Islamic Revolution, causing seminaries` disability in the management of social issues, strengthening opposing currents in seminaries, increasing ambiguity, lack of strategic intelligence and expanding and promoting reactionary in seminaries.