Prolonged tensions in the Middle East and its symmetry with recent global developments have left the region with a new wave of nation-state-building over a rift of conflict. Conflicts that began with the incomplete process of state-nation-building in the last century in the Middle East and appeared and spread in national-regional levels in various forms, and reached the peak of the nation-state conflict with IRI and continued with the popular movements at the beginning of the third millennium. Continued. This article, as a descriptive and analytical research, seeks to answer the question: How do national and regional conflicts and the state-nation-building process in the Middle East relate to each other? The results of the studies show that there is a bilateral and inverse relationship between the two. In the sense that the incomplete process of state-nation-building has created numerous conflicts that have led to the continuation of this flawed process and ultimately to the intensification and expansion of national and regional conflicts.