Takfiri currents are one of the main problems in the Islamic world and have caused insecurity, violence, genocide and fratricide. These currents have posed many challenges to the discourse of the Islamic Revolution by having features such as superficiality, irrationalism, opposing unity, violence-based state, and disregarding Istikbar. The study has intended to survey the question: what may be taken as the cultural challenges of the Takfiri currents against the discourse of the Islamic Revolution and the strategies to deal with it? Cultural challenges include such cases as causing doubt in beliefs, destroying the context of dialogue, destroying the effects of Islamic civilization, weakening the intellectual and ideological position of the Islamic Revolution, and so on. To oppose these challenges, strategies are offered, including an accurate explanation of the discourse of the Islamic Revolution, awareness of Takfiri currents, cultural diplomacy, the approximation of Islamic religions, and efforts to form a scientific movement. To answer the paper's question, Thomas A. Spragens' "theory of crisis" has been used.